Hanahan, D. and R.A. Weinberg, Hallmarks of cancer: the next generation. Cell, 2011. 144(5): p. 646-74.
Fearon, E.R. and B. Vogelstein, A genetic model for colorectal tumorigenesis. Cell, 1990. 61(5): p. 759-67.
Smit, W.L., et al., Driver mutations of the adenoma-carcinoma sequence govern the intestinal epithelial global translational capacity. Proc Natl Acad Sci U S A, 2020. 117(41): p. 25560-25570.
Armaghany, T., et al., Genetic alterations in colorectal cancer. Gastrointest Cancer Res, 2012. 5(1): p. 19-27.
Cox, A.D., et al., Drugging the undruggable RAS: Mission possible? Nat Rev Drug Discov, 2014. 13(11): p. 828-51.
De Filippo, C., et al., Mutations of the APC gene in human sporadic colorectal cancers. Scand J Gastroenterol, 2002. 37(9): p. 1048-53.
Zhu, G., et al., Role of oncogenic KRAS in the prognosis, diagnosis and treatment of colorectal cancer. Mol Cancer, 2021. 20(1): p. 143.
NIH. Common Cancer Types. [cited 2023 18 Jan]; Available from: https://www.cancer.gov/types/common-cancers.
Society, A.C. Colorectal Cancer Facts & Figures 2020-2022. [cited 2023 Jan 24].
Thompson, C.A., T. Begi, and H. Parada, Jr., Alarming recent rises in early-onset colorectal cancer. Cancer, 2022. 128(2): p. 230-233.
Bailey, C.E., et al., Increasing disparities in the age-related incidences of colon and rectal cancers in the United States, 1975-2010. JAMA Surg, 2015. 150(1): p. 17-22.
AlZaabi, A., et al., Early onset colorectal cancer: Challenges across the cancer care continuum. Ann Med Surg (Lond), 2022. 82: p. 104453.
Wallace, M.B., et al., Impact of Artificial Intelligence on Miss Rate of Colorectal Neoplasia. Gastroenterology, 2022. 163(1): p. 295-304.e5.
Wiertsema, S.P., et al., The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies. Nutrients, 2021. 13(3).
Iacob, S., D.G. Iacob, and L.M. Luminos, Intestinal Microbiota as a Host Defense Mechanism to Infectious Threats. Front Microbiol, 2018. 9: p. 3328.
Puschhof, J. and C.L. Sears, Microbial metabolites damage DNA. Science, 2022. 378(6618): p. 358-359.
School, H.M. Can gut bacteria improve your health? 2016 [cited 2023 24 Jan]; Available from: https://www.health.harvard.edu/staying-healthy/can-gut-bacteria-improve-your-health.
Costerton, J.W., P.S. Stewart, and E.P. Greenberg, Bacterial biofilms: a common cause of persistent infections. Science, 1999. 284(5418): p. 1318-22.
Fux, C.A., et al., Survival strategies of infectious biofilms. Trends Microbiol, 2005. 13(1): p. 34-40.
Sharma, D., L. Misba, and A.U. Khan, Antibiotics versus biofilm: an emerging battleground in microbial communities. Antimicrob Resist Infect Control, 2019. 8: p. 76.
Stewart, P.S. and J.W. Costerton, Antibiotic resistance of bacteria in biofilms. Lancet, 2001. 358(9276): p. 135-8.
Dejea, C.M., et al., Microbiota organization is a distinct feature of proximal colorectal cancers. Proc Natl Acad Sci U S A, 2014. 111(51): p. 18321-6.
Swidsinski, A., et al., Comparative study of the intestinal mucus barrier in normal and inflamed colon. Gut, 2007. 56(3): p. 343-50.
Drewes, J.L., et al., High-resolution bacterial 16S rRNA gene profile meta-analysis and biofilm status reveal common colorectal cancer consortia. NPJ Biofilms Microbiomes, 2017. 3: p. 34.
Ettinger, S., Chapter 1 - Obesity and Metabolic Syndrome, in Nutritional Pathophysiology of Obesity and its Comorbidities, S. Ettinger, Editor. 2017, Academic Press. p. 1-26.